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The glutamate produced from glutamine is converted to 2-oxoglutarate (-ketoglutarate) via the action of glutamate dehydrogenase (making glutamine a glucogenic amino acid) and yielding another mole of NH 4 +

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Glutathione is given intravenously because this route delivers the antioxidant directly into the bloodstream, bypassing digestive breakdown that destroys nearly all of an oral dose