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[50] [51] [52] In 2011 there were about 7 million adult e-cigarette users globally, increasing to 68 million in 2020 compared with 1 } : CS1 maint: multiple names: authors list (link) "Nicotine vaping in England: an evidence update including health risks and perceptions, September 2022

American Spirit cigarettes deliver an average of 3.3 mg per cigarette

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They havent been studied in a rigorous manner. Rizzo also notes that studies on e-cigarettes are especially challenging due to difficulties in making direct comparisons

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