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The copper component of GHK-Cu works through a different mechanism than pharmaceutical inhibitors
Phadungsil W, Pumpa S, Sirisabhabhorn K, Geadkaew-Krenc A, Grams R, Mungthin M, Ruang-Areerate T, Adisakwattana P, Labbunruang N, Martviset P
So in theory, the free copper is definitely a potent 5AR inhibitor and if free copper concentrations reach a decent level in the scalp, you can expect a big inhibition of local 5AR1