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Fast forward to 2010 when the FDA opened a public comment period seeking input from anyone interested in helping FDA develop guidelines for an Approved Tobacco Retailer Training Program. We Card submitted lengthy suggestions on what best practices should be as did many others

Nature 2010;463:4953

They almost always trace back to documentation that does not support the three clinical elements the code requires: (1) nicotine dependence rather than mere tobacco use, (2) cigarettes as the specific substance, and (3) the absence of withdrawal and the absence of remission

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