Hepcidin transcription regulation is linked to the pathways that react to mitogen stimulation and nutritional status through components of Ras/RAF MAPK and mTOR signaling
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American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 288(2), R374-R383
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However, in line with the specificity of CPA, the C-terminal residues of the L585I, L585M, and L585V variants were cleaved in vitro upon exposure to the enzyme for 5 hours at 37 C, as confirmed by liquid chromatography with tandem mass spectrometry (LC-MS/MS) analysis of the C-terminal peptides (Supplementary Table 1)
= difference in BP between two quintile groups (Q5, fifth quintile