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These MAPKs, including ERK and JNK, are serine/threonine protein kinases that regulate cell proliferation, differentiation, and apoptosis in tumorigenesis
Most of the time, there are no accurate symptoms or tests to determine whether or not there is VOC-related discomfort [46]
[DOI] [PMC free article] [PubMed] [Google Scholar] Nies D
And perhaps most importantly, the rate of treatment discontinuation, which reveals how tolerable each treatment is in the real world rather than in the controlled environment of separate trials
Spatial transcriptomics combined with single-cell RNA sequencing identified high expression levels of ferroptosis-related genes, including TFRC, NCO4, and SLC3A2, in granulosa cells of patients with ovarian senescence, while GPX4 expression was notably low (Lin et al., 2023)
Helping to maintain a healthy internal clock (circadian rhythm)
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