Despite the multifunctionality of these proteins, GSTs are best known for their ability to transfer the tripeptide gamma-glutamyl-cysteinyl-glycine, also known as glutathione (GSH) to a wide variety of highly genotoxic and cell-damaging molecules, either directly occurred from the extracellular environment or from the intracellular detoxification metabolism
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doi: 10.2147/CIA.S163275, 42
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Glutathione-depleting gold nanoclusters for enhanced cancer radiotherapy through synergistic external and internal regulations
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