does glutathione darken skin can Glutathione For Skin Lightening;I Used It,Experts Advise On Glutathione Usage Glutathione for Hyperpigmentation: How It

by Chris Kresser [ 2

doi: 10.1016/j.jaut.2010.07.003 168 GherardiRKCoquetMCherinPBelecLMorettoPDreyfusPAet al

A controlled clinical trial of 71 women with mild to moderate photo-damage found that twice-daily application of a GHK-Cu cream over twelve weeks produced statistically significant improvements in skin laxity, firmness, clarity, and overall appearance compared to both placebo and a vitamin C control group

The cycle above utilizes key antioxidants such as glutathione (GSH) and ascorbate (AsA) and enzymes such as dehydroascorbate reductase (DHAR), glutathione reductase (GR), monodehydroascorbate reductase (MDHAR), and ascorbate peroxidase (APX)

Many users continue at a lower maintenance dose after the initial loading phase

Sources: Weschawalit, S., Thongthip, S., Phutrakool, P., & Asawanonda, P