Intranasal drug delivery: How, why and what for
"The antidepressant effect of an antiulcer pentadecapeptide BPC 157 in Porsolt's test and chronic unpredictable stress in rats." Journal of Physiology Paris
Dihexa , a new and innovative kind of peptide, has been shown to have the potential to restore cognitive ability, improve memory, and promote the creation of new synaptic connections in the brain, which may be able to aid those who suffer from issues or disorders of the brain and help them to regain their mental capacity
The Phase 2 trial enrolled participants with obesity and evaluated multiple dose levels over 48 weeks: 1 mg dose: 8.7% average body weight reduction 4 mg dose (escalated from 2 mg): 17.1% average body weight reduction 8 mg dose (escalated from 2 mg): 22.8% average body weight reduction 12 mg dose (escalated from 2 mg): 24.2% average body weight reduction Placebo: 2.1% average body weight reduction Those Phase 2 numbers were striking enough
rotate injection sites systematically [3]
Because water is the solvent, these two p K a values have a different meaning than the values determined for typical solute acids