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The following is taken from the section, "How should treatment be given", from the peer-reviewed medical-journal article, "The Many Faces of Cobalamin (Vitamin B12) Deficiency": [Start quote] For parenteral therapy in cases of megaloblastic anemia, it has been advised to administer 1000 mg hydroxocobalamin IM twice weekly for a period of 5 weeks, and the dose is reduced to 1000 mg IM every 2 months thereafter

J Neurosci 16 : 53245333

As always, its critical to choose a reputable brand and not just buy a random curcumin supplement at Costco or Amazon

Serious side effects are rare in small studies, but risks include: Injectionsite infection or allergic reaction

Seyssel K, Alligier M, Meugnier E, Chanseaume E, Loizon E, Canto C, et al

Beyond-use dating : The period for which a reconstituted solution may be stored and used is defined by the SmPC and local pharmacy policy not by generic rules