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In aged human pinealocytes, Epitalon selectively safeguarded cells from degenerative changes, suggesting a tissue-specific rejuvenating effect on the very gland responsible for circadian control

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107 A randomized controlled trial included 102 tinnitus patients who received either melatonin (3 mg nightly) plus sulodexide, melatonin (3 mg nightly) alone, or no treatment for 80 days

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The initial changes are often subtle, such as improved energy or smoother skin texture