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The treatment consists of natural compounds already present in the body, which may help minimize potential side effects [2]

Several in vitro models such as primary trophoblast cells, placental immortal cell lines, and placental explants have frequently been used [26,27,28]

(476) conducted a study demonstrating that isolated polyphenols from Pinus koraiensis pinecones have an anti-cancer impact on colon cancer cells via stimulating death via caspase activation

CD, however, can involve any location in the gastrointestinal tract, from mouth to anus

Butler et al., 2025)

Additionally, McConkey et al., in 1967, observed the occurrence of transparent skin that was associated with a decrease in dermal collagen in postmenopausal women [21]