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Sometimes the inflammation is subtle and appears as puffiness around the knees, wrists, knuckles, or ankles

Elderly patients should call 999 immediately if they experience difficulty breathing, throat tightness, facial swelling, or widespread rash after B12 administration, as these may indicate a rare but serious allergic reaction requiring emergency treatment

Water retention Some puffiness or bloating, especially in hands and face, as IGF-1 causes cells to hold more water

CNNs John Bonifield contributed to this report.

KPV peptide: targeting gut inflammation KPV is a tripeptide composed of lysine, proline, and valine