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doi: 10.1016/S0021-9258(17)40500-X 60 ShalataA.MittovaV.VolokitaM.GuyM.TalM

Furthermore, Alterations in enzymes such as PKM2 and shifts in metabolic pathways (e.g., from TCA cycle to PPP) play a critical role in myofibroblast functionality and survival, thus influencing fibrosis progression

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Next, least absolute shrinkage and selection operator (LASSO) Cox regression analysis was conducted utilizing the function glmnet of R (version 4.17) to construct a prognostic model