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In blood pressure studies, the peptide did not affect basal blood pressure but counteracted both L-NAME-induced hypertension and L-arginine-induced hypotension

Stellpflug SJ , Gardner RL , Leroy JM , Ellsworth H , Zwank MD

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Approximately 33% of patients had two or more tests during this time period

These can include mild reactions such as irritation at the subcutaneous injection site, headaches, dizziness, or gastrointestinal discomfort

The rats were maintained in an animal room with an air-conditioned barrier system at an ambient temperature of 25C 2C, relative humidity of 50% 10%, and a 12 h light/dark cycle