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breve NCIM 5671 had better antiarthritic effects in the rat model than the other bifidobacterial species studied, suggesting that the effect is strain-dependent, and these strains should be further explored for their putative positive impact on RA treatment (Table 1 summarizes the characteristics and main findings regarding probiotic effects on RA in preclinical studies

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However, chronic exposure can promote stable increases in these metabolic phenotypes, as evidenced by our resistant organoid models (Extended Data Fig

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Mutations in genes encoding other components of the PDHc, including the PDHB gene and the DLAT gene, have been shown to be associated with PDH deficiency syndromes

Analyses of in vivo TIFs revealed significant differences in aminothiol levels between trametinib and combination therapy