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According to the latest review, 41 GERD prevalence estimates range from 18.1% to 27.8% in North America, 8.8% to 25.9% in Europe, 2.5% to 7.8% in East Asia, 8.7% to 33.1% in the Middle East, 11.6% in Australia, and 23.0% in South America

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So, ipramarylin is the most commonly discussed one in this type two category

PMID 14279251

Physicochemical Profile Appearance: White to off-white lyophilized powders Solubility: Soluble in sterile water and aqueous buffers Stability: Stable under dry, refrigerated conditions