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Adjei AA, Gaedigk A, Simon SD, Weinshilboum RM, Leeder JS: Interindividual variability in acetaminophen sulfation by human fetal liver: implications for pharmacogenetic investigations of drug-induced birth defects

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10.1006/gyno.1994.1055 Gynecol

In humans, the biotin-requiring enzymes include acetyl-CoA carboxylase (ACC: humans express two distinct ACC genes), pyruvate carboxylase (PC), propionyl-CoA carboxylase (PCC), and 3-methylcrotonyl-CoA carboxylase (3MCC)

Still, these possibilities are encouraging for many families

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