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Research now shows that treatments such as photobiomodulation (light therapy), extracorporeal shockwave therapy, electrical stimulation, vibration therapy, and specific nutritional supplements can improve pain, restore sensation, and even improve nerve conduction

Hydration: Keeps the skin hydrated and plump, reducing the appearance of fine lines and wrinkles

This mathematical relationship is why the manufacturer sets both a time limit and a temperature limit for room temperature storage

6 De VendittisA.MarcoS.Di MaroA.ChamberyA.AlbinoA.MasulloM.et al (2012)

There is no ethical way to study this, so the only responsible course of action is total avoidance