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Late assessment: rats with ligated left colic artery and vein that underwent additional colon obstruction for three days (IC + OB rats) In these experiments, treatments were administered to blood-deprived colon segments that had additionally been challenged with ring obstruction

Their interaction with biological systems involved in healing and protection makes them highly relevant for controlled scientific investigations

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Accordingly, the present invention should not be limited to the embodiments as described above, but should further include all modifications and equivalents thereof within the spirit and scope of the description provided herein