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Through a comprehensive analysis of histone modifications in lesional skin from both psoriasis patients and mice, the significantly increased level of histone acetylation at H4 lysine 16 (H4K16ac) in macrophages was found, which was positively correlated with the accumulation of self-RNA in the dermis and psoriasis pathology

What is the time needed to see any change

This concentration helps protect against photoaging and supports the skin's natural repair processes

A similar concept was used by Hu et al

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