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Choline metabolism underpins macrophage IL-4 polarization and RELMalpha up-regulation in helminth infection

Less tryptophan for serotonin More quinolinic acid (which upregulates NMDA receptors and anxiety) Increased depressive symptoms in chronic illness This is why so many patients with gut issues, autoimmunity, or Lyme experience mood changes

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moderate hepatic impairment, n = 7