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Contribution of oxidative stress and impaired biogenesis of pancreatic -cells to type 2 diabetes

Figure 1 2.1 Overproduction of ROS One hallmark feature of IBD is the overproduction of ROS, which causes dysregulation of signal transduction, an inflammatory response, and DNA damage, all of which contribute to the progression and deterioration of the disease ( 2), nitric oxide (NO), hydroxyl radical (-0H), hydroperoxyl radical (O 2 H), hydrogen peroxide (H 2 O 2 ), and singlet oxygen ( 2.2 Damage to biomolecules ROS can damage various cell biomolecules, including lipids, proteins, and DNA

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Subjectively, adequate B12 manifests as maintained energy levels, absence of neurological symptoms like numbness or tingling, and normal cognitive function

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