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Decreased dopamine signaling through overeating can lead to dopamine adaptation and sometimes behavioral changes

Nature Cell Biology , 24 (6), 896905

The pathogenesis of MASH primarily involves insulin resistance, dysregulated lipid metabolism, oxidative stress, and chronic low-grade inflammation, among which collectively induce an immune response in the liver, ultimately causing inflammation and tissue damage

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While many suggest that a deficiency in vitamin B12 can cause weight gain, the opposite is actually true