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This enhanced in vitro potency translated into in vivo efficacy, where a single 3 mg/kg dose of the BsADC achieved 30% tumor growth inhibition in JIMT-1 xenograft models, matching the efficacy of the combined monospecific ADCs
In: MoorePKWhitemanM editors
Disclosures A preliminary version of this manuscript was published in the Journal of Neurology and Neurophysiology References Regland B, et al
Absorption can be inhibited by poorly functioning kidneys, cigarette smoke, nitrous oxide used for anaesthesia, heating food in a microwave or cooker and some medications, including Metformin (for diabetes), anticonvulsants and proton pump inhibitors (PPIs)
Moreover, ensuring consistent quality, selectivity for specific heavy metal ions, and reliable separation and purification after each treatment cycle remains unresolved