When NNMT is overactive as it tends to be in fat tissue, and increasingly with age and obesity it siphons off the very raw material your cells need to keep NAD+ topped up
The rationale behind this stack is that 5-amino-1mq enhances cellular fat metabolism, AOD-9604 promotes lipolysis through growth hormone receptor activation, and the secretagogue compound stimulates natural growth hormone release
This is not specific to tirzepatide or AOD 9604 but rather a consequence of rapid weight loss itself, known as telogen effluvium
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[DOI] [PMC free article] [PubMed] [Google Scholar] 108.Cannone V, Cabassi A, Volpi R, Burnett JC
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