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Description

The DSS-induced UC mouse model is a short-term model

Following oral administration, the area under the concentration-time curve was much lower (9 nmol/min/mL vs 137 nmol/min/mL)

PMID: 58 SiemersKMKleinAKBaackML

Conclusion Retatrutide is a single peptide conjugated to a lipid diacid molecule

Yuen et al., 2018)

It reduces post-injury fibrosis by modulating the expression of matrix metalloproteinases (MMPs), promotes the formation of new blood vessels, and stimulates muscle fiber regeneration