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Supplementary material The Supplementary Material for this article can be found onlineat: References 1 HenleySJWardEMScottSMaJAndersonRNFirthAUet al

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Active viral infectionHistory of allergy to penicillin, aminoglycosides, or macrolide antibioticsCurrently undergoing treatment for malignant tumorsVaccinated within the past monthPlanning to receive COVID-19 or influenza vaccine within the next two weeksSubject to doping testsPregnant or possibly pregnantUnable to provide consent for any reasonUsing isotretinoin or within one month after stopping isotretinoinDeemed inappropriate for use by a physician for any other reasonUsing topical hydroquinoneUsing topical medication for atopic dermatitisUsing topical retinolUsing topical acne medication Please inform your physician of all your medical history and any medications you are currently taking

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