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The absence of -catenin in cardiac fibroblasts can reduce myocardial hypertrophy and post-TAC fibrosis and improve cardiac function

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Further, postmortem alcoholic brains have shown increased TLR2, TLR3, and TLR4 expression in the orbitofrontal cortex, which correlates with BBB integrity loss (Rubio-Araiz et al., 2017)