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There are no other absolute contraindications reported for hydroxocobalamin use in deficiency states, but caution is advised in individuals with conditions such as early Lebers optic neuropathy (a rare hereditary optic atrophy) due to the theoretical risk of worsening vision

Autoimmune conditions such as pernicious anaemia

How to Treat B12 Deficiency The best treatment for a B12 deficiency depends in part on the cause