Exosomes from osteoarthritic fibroblast-like synoviocytes promote cartilage ferroptosis and damage via delivering microrna-19b-3p to target slc7a11 in osteoarthritis
[DOI] [PMC free article] [PubMed] [Google Scholar] 249.Caprara C., Thiersch M., Lange C., Joly S., Samardzija M., Grimm C
doi:10.1016/j.bbrc.2016.11.089
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It is released in pulses, mostly at night during deep sleep, with the largest pulse typically occurring in the first 60 to 90 minutes after sleep onset