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Severe kidney impairment Limited data

FXR agonists for MASH therapy: lessons and perspectives from obeticholic acid

GSH is known for its multiple physiological functions as an antioxidant against ROS and free radicals in detoxification of xenobiotic compounds [24, 25, 26, 27, 28]

The two published human studies (both DAC) The pivotal human data come from a randomized, double-blind, placebo-controlled ascending-dose study by Teichman and colleagues in healthy adults