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It appears more selective and possibly safer than older senolytic approaches

The influence of estrogen on hippocampal cell proliferation is mediated through estrogen receptors (ER) as estradiol-induced cell proliferation in the hippocampus can be inhibited by ER antagonist [142], whereas ER agonist enhances cell proliferation [143]

BPC-157 increases growth hormone receptors in fibroblasts, extending their lifespan and enhancing their ability to promote the regeneration of soft tissues [3]

These factors contribute to more effective B12 repletion and maintained levels

The clinical benefit was evaluated by comparing parameters qualifying the response to treatment (change from baseline UPDRS motor score) estimated for SC and SL administration over the interval 0 to 90 min post-dose using trial simulations