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As glutathione levels decline with age, cells become more vulnerable to damage

2.9 Glutathione content measurement Tissue samples (1.5 g) were ground in 2 mL 60 mmol L 1 sodium phosphate buffer (pH 7.0), and refrigerated centrifugation was performed at 12,000 g for 15 min, after which 100 L of supernatant was obtained

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Furthermore, another recently described player involved in GSH catabolism is the specific cytoplasmic GSH-degrading enzyme CHAC1 (59)

The body produces a larger protein called Body Protection Compound naturally

Genistein suppresses GLUT1 and HK2 expression by downregulating HIF-1 (106), induces cell cycle arrest, and reduces the invasive capacity of CRC cells (107)