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High levels of HMGB1 have been shown in acute lung injury caused by infectious and severe COVID-19 patients, therefore, it could be a therapeutic target for patients with severe COVID-19 [324]

These in turn are affected by the combined impact of costliness, awareness about health risks, declining social acceptability of smoking, campaigns encouraging quitting, improved treatments for tobacco dependence, greatly reduced opportunities for smoking as well as use of other nicotine products

doi: 10.3389/ftox.2022.958414

Rijksinstituut voor Volksgezondheid en Milieu RIVM Torres S, Merino C, Paton B et al (2018) Biomarkers of exposure to secondhand and thirdhand tobacco smoke: recent advances and future perspectives

Aerosol from a candidate modified risk tobacco product has reduced effects on chemotaxis and transendothelial migration compared to combustion of conventional cigarettes

If youre taking them out with you, use a hard case