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3 Immunohistochemistry of interleukin-1 (IL-1) in the dorsal root ganglion (DRG) and spinal cord (SC) at (A) 5 min (representative value of phase 1) and (B) 35 min (representative value of phase 2) Graph (bottom) represents the number of immunostained cells in the DRG and SC (mean SD)

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, a free radical scavenger (17, 29)) against the early paracetamol lesions development, and even more importantly, when the original damaging process induced by an extreme paracetamol over-dose was highly advanced

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