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The administration of NAC within the appropriate timeframe reduces the risk of hepatotoxicity and significantly improves patient outcomes

doi: 10.1038/s41419-021-04306-2 88

Since CoQ10 is not water soluble it needs fat to be absorbed efficiently, ideally with a meal that contains a form of fat

Cortisol affects neuronal mitochondrial function in a biphasic manner : Low, normal levels of cortisol increase mitochondrial function Chronically high levels of cortisol decrease mitochondrial function.[ref] Chronic stress alters cortisol levels and thus can affect mitochondrial function in the brain

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