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Withdrawal symptoms, including irritability, anxiety, and the constant hankering for a nicotine hit, often pop up when nicotine intake is cut

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The design reflects a rebellious yet playful spirit, making it perfect for fans who appreciate clever graphic art and nostalgic references

Smoking the drug, Iloreta noted, would be a particular concern, due to the tiny inhaled particles in the smoke -- which could end up impairing the natural "housekeeping system" in the nose

JAMA 271 , 17521759 (1994)

People who smoke will often have a long-lasting cough