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As NADPH is insufficient in G6PD-deficient RBCs, the increased ROS are not eliminated effectively and thus cause damage to the RBCs

Similarly, hyperactivity due to elevated dopamine content in the synapse has been reported in mice lacking DAT [48] and rats with pharmacological blockade of DAT [49, 50]

Persistence of mixed chimerism in patients transplanted for the treatment of thalassemia

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