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But the jump from C57BL/6 mice to humans involves differences in metabolic rate, NNMT tissue distribution, adipose tissue physiology, and drug metabolism that preclinical data cannot address

NAD+ also supports DNA repair, cellular stress responses, and the regulation of inflammation, as well as the function of key longevity proteins called sirtuins

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Application in Research: Where Each Compound Shines Digging deeper, where do we see these compounds making the biggest impact in the lab