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[165] Additionally, research on the neurobiological effects of physical exercise suggests that daily aerobic exercise, especially endurance exercise (e.g., marathon running), prevents the development of drug addiction and is an effective adjunct therapy (i.e., a supplemental treatment) for amphetamine addiction

Psychiatry 172 , 1731 (2015)

, Koplin, R

The 5% concentration, approved for men, demonstrates more significant clinical benefits than the 2% solution commonly recommended for women