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Biol Psychiatry (1998) 44:8897.10.1016/S0006-3223(98)00138-3 167 ChanaGLandauSBeasleyCEverallIPCotterD

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Transfection of Cyp2E1 [145] or induction of Cyp2E1 by dimethyl sulfoxide (DMSO) [139], can restore at least in part the metabolic capacity of HepG2 cells but the overall gene expression profile of HepG2 cells shows low similarity to primary human hepatocytes [146, 147]