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Their best known role is as cell housekeepers engaged in the detoxification of xenobiotics

Mesna tablets were approved by the FDA in 2002 as a preventive agent to reduce the occurrence of a complication called ifosfamide-induced hemorrhagic cystitis, in which the bladder becomes inflamed and bleeds (Cohen 2002

In particular, GSH catalytically detoxifies from hydroperoxides, peroxynitrite, and lipid peroxides and directly scavenges various oxidant molecules, like superoxide anion, hydroxyl radical, nitric oxide, and carbon radicals

PMID: 24526250

There is also a study by La Roche Posay (belongs to L'Oreal) that examined the anti-aging effects of 5% Vitamin C combined with 0.1% Madecassoside

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