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Results from this intermittent protocol showed comparable or superior outcomes to daily dosing in measures of cognitive recovery and neuronal survival, suggesting that more frequent administration doesn't necessarily produce proportionally greater effects

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Intramuscular injections of B12 are administered during the first stage of the test, an hour after the patient takes an oral dose of radiolabeled vitamin B12

doi:10.3389/fpsyt.2018.00669 Morris, C.R., HamiltonReeves, J., Martindale, R.G., Sarav, M

As with any medical treatment, there may be minor risks, like bruising or temporary discomfort at the injection site, but these are typically rare and mild