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Semaglutide for cardiovascular event reduction in people with overweight or obesity: SELECT study baseline characteristics

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doi: 10.3390/nu8020078

Although endothelial activation and redox signaling compose a normal host defense, when this activation is sustained, chronic production of ROS may exceed the capacity of cellular enzymatic and nonenzymatic antioxidant defenses [49], contributing to triggering vascular diseases such as atherosclerosis or peripheral artery disease [102, 103]

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This theory suggests that sleep is one of the many antioxidant defense systems employed in mammalian species that restores the redox status of cells and tissues to its equilibrium