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Your pituitary (the small gland at the base of your brain that releases GH) isnt held in a prolonged on state, it pulses, then resets, then is ready for the next natural signal

Gaut JP, Byun J, Tran HD, Lauber WM, Carroll JA, Hotchkiss RS, et al

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This decline is also associated with a decreased ability of these cells to migrate to lymph nodes, a crucial step for T cell activation [252, 253]

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