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Hitsman, B

In this latest systematic review, people having a first episode of psychosis were three times more likely to be smokers than nonsmokers

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31,32 Also, patients with schizophrenia or schizophrenia-like disorders have an increased vulnerability to compulsive use of drugs

Based on their findings, the authors questioned the self-medication theory and proposed instead that nicotine may be having an effect that creates the conditions for psychosis, possibly on the dopamine system