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Why This Matters in MCAS In MCAS, chronic mast-cell activation in the gut, brain, and connective tissues can damage the enteric and autonomic nervous systems, contributing to symptoms such as nausea, motility issues, dysautonomia, and neuroinflammatory fatigue

Safety and Precautions BPC-157 is generally safe when used as directed

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On the gastrointestinal front, literature has described mucosal barrier protection via modulation of endogenous prostaglandin (PGE2) and heat shock proteins (HSP70/90)

Individuals with a deficiency in vitamin B12 may experience symptoms such as fatigue, weakness, and changes in weight or metabolism