Skin penetration, plasma binding, and copper-pool dynamics complicate dose extrapolation
Older adults may have thinner skin that is more prone to bruising
(See also point 3 and 4, note 2) Supplementation (1000 mcg hydro(xo)cobalamine B12 injections, 2 times a week intramuscularly or deep subcutaneously for five weeks, or once a week for ten weeks) is primarily done when deficiency has been diagnosed
Can this test be done by anyone
If the patient is suspected to be sensitive to cobalt or other components of cobalamin, an intradermal test dose is recommended
However, oral zinc may cause gastrointestinal discomfort, nausea, or poor absorptionespecially during illness