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Through its ability to block NOTCH1 maturation, CHAC1/BOTCH was identified as Neuroprotective Gene 7 (NPG7) due to its protective effects in neuronal contexts
3.2 Lipid metabolism Aberrant lipid metabolism may enhance lipid peroxidation and induce ferroptosis by altering the lipid compositions of biomembranes (Harayama and Riezman, 2018)
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